Ceftizoxime in the treatment of uncomplicated gonorrhoea.
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منابع مشابه
Ceftizoxime in the treatment of uncomplicated gonorrhoea.
A total of 74 men and 26 women with uncomplicated gonorrhoea were treated with ceftizoxime sodium 0.5 g intramuscularly. The cure rate was 99% and included successful treatment of four infections due to beta-lactamase producing organisms. The minimum inhibitory concentrations (MICs) of ceftizoxime in vitro were very much lower than those of penicillin and cefuroxime, and side effects were minim...
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Acrosoxacin was given as a single 300 mg oral dose to 105 patients with acute gonorrhoea. Of the 100 patients followed completely there was a 93% cure rate and 33% of men developed postgonococcal urethritis (PGU). This compared with a 97% cure and 30% PGU with 2 megaunits penicillin. The in vitro activity of acrosoxacin in Nottingham against strains of Neisseria gonorrhoeae showed that it was a...
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An open study was designed primarily to evaluate the efficacy of rosoxacin in the treatment of gonorrhoea caused by penicillinase producing Neisseria gonorrhoeae (PPNG) and non-PPNG strains. A total of 199 patients (99 men and 100 women) satisfactorily completed follow up examinations, 50 men and 50 women having received rosoxacin 300 mg orally and the remainder having received kanamycin 2 g in...
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Between 3 January and 4 March 1983 we treated 200 male patients diagnosed as having uncomplicated gonococcal urethritis with one of two regimens. They were divided into two groups and randomly assigned to treatment with either 2 g spectinomycin administered intramuscularly (group A) or 300 mg rosoxacin by mouth (group B). Of 187 isolates tested for the production of beta-lactamase, 101 (54%) we...
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In 1960 spectinomycin, a new broad spectrum antibiotic, was released for clinical investigation and it was shown that the administration of 2 g. of the sulphate salt was effective therapy in acute gonorrhoea yielding cure rates of approximately 87 to 95 per cent. in males. The cure rate in females was 92 per cent. with a 3 g. dose (Laird and Taylor, 1962; Wilcox, 1963; Tiedemann, Hackney, and P...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1984
ISSN: 1368-4973
DOI: 10.1136/sti.60.2.90